Which group do the antibodies involved in allergic reactions belong to?

Study for the Rutgers Anatomy and Physiology II exam. Review with comprehensive questions, flashcards, and detailed explanations. Enhance your understanding of key concepts!

Antibodies involved in allergic reactions belong to the IgE group. This class of immunoglobulin is specifically associated with the body’s response to allergens, which are usually harmless substances that trigger an exaggerated immune response. When an individual is exposed to an allergen, IgE antibodies bind to it and trigger the release of histamine and other chemicals from mast cells and basophils, leading to the symptoms commonly seen in allergic reactions such as hives, asthma, or anaphylaxis.

In contrast, other antibody classes serve different roles in the immune response. For instance, IgG is the most abundant antibody in serum and plays a crucial role in long-term immunity and neutralizing pathogens. IgA is primarily found in mucosal areas, such as the gut and respiratory tract, providing a frontline defense against pathogens entering through these surfaces. IgM is the first antibody produced in response to an infection and is effective in forming complexes that facilitate the elimination of pathogens.

Thus, the unique association of IgE with allergic responses clearly distinguishes it as the correct answer regarding the antibodies involved in allergic reactions.

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