What is commonly associated with X-linked disorders?

X-linked disorders are typically associated with more frequent expression in males due to the presence of only one X chromosome in males (XY), whereas females have two X chromosomes (XX). Because of this genetic configuration, if a male inherits an X chromosome carrying a recessive allele for a disorder, he will express the trait since he does not have a second X chromosome that could potentially carry a normal allele to counteract the effect. In contrast, females would need two copies of the allele (one on each X chromosome) to express the disorder, which makes it less common for females to be affected. Therefore, X-linked disorders manifest more frequently in males than in females, which is a fundamental concept in understanding how these genetic disorders operate.